Molecular Epidemiology of Mycobacterium abscessus Isolates Recovered from German Cystic Fibrosis Patients
Year: 2022
Type: article
Study design: Observational Study
Abstract: Mycobacterium abscessus is a major respiratory pathogen in cystic fibrosis (CF) patients. Recently it has been shown that dominant global clonal complexes (DCCs) have spread worldwide among CF patients. This study investigated the epidemiological situation of M. abscessus among CF patients in Germany by performing whole-genome sequencing (WGS) of a set of 154 M. abscessus from 123 German patients treated in 14 CF centers. This is the largest study investigating the phylogenetic relationship of M. abscessus CF isolates in Germany.
Source: Microbiology Spectrum
Authors: Nils Wetzstein, Margo Diricks, Thomas A. Kohl, Thomas A. Wichelhaus, Sönke Andres, Laura Paulowski, Carsten Schwarz, Astrid Lewin, Jan Kehrmann, Barbara C. Kahl, Karl Dichtl, Christian Hügel, Olaf Eickmeier, Christina Smaczny, Annika Schmidt, Stefan Zimmermann, Lutz Nährlich, Sylvia Hafkemeyer, Stefan Niemann, Florian P. Maurer, Michael Hogardt
Institutions: Goethe University Frankfurt, University Hospital Frankfurt, German Center for Infection Research, Research Center Borstel - Leibniz Lung Center, Charité – Universitätsmedizin Berlin, Robert Koch Institute, Essen University Hospital, University of Duisburg-Essen, University Hospital Münster, Max-von-Pettenkofer-Institut für Hygiene und Medizinische Mikrobiologie, Ludwig-Maximilians-Universität München, Universitätsklinikum Tübingen, University of Tübingen, University Hospital Heidelberg, Justus-Liebig-Universität Gießen, The Cystic Fibrosis Institute, University Medical Center Hamburg-Eppendorf
Language: English
Subfield: Epidemiology
Field: Medicine
Domain: Health Sciences
Open Access status: gold
Estimated APC paid: $2,206
Awards: G165400314, G8216014321
OpenAlex ID: W4290649039