Work

Autoantibody mimicry of hormone action at the thyrotropin receptor

Year: 2022

Type: article

Source: Nature

DOI: 10.1038/s41586-022-05159-1

Authors: Bryan Faust, Christian B. Billesbølle, Carl-Mikael Suomivuori, Isha Singh, Kaihua Zhang, Nicholas Hoppe, Antonio F. M. Pinto, Jolene K. Diedrich, Yagmur Muftuoglu, Mariusz W. Szkudlinski, Alan Saghatelian, Ron O. Dror, Yifan Cheng, Aashish Manglik

Institutions: University of California, San Francisco, Stanford Medicine, Stanford University, Salk Institute for Biological Studies, Trophogen (United States), Howard Hughes Medical Institute, Chan Zuckerberg Biohub San Francisco

Language: English

Topic: Receptor Mechanisms and Signaling

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

Funders: Howard Hughes Medical Institute, National Institutes of Health, National Cancer Institute, National Institute of General Medical Sciences

Awards: Molecular Biophysics Training Grant, The Stanford-SLAC CryoEM Center, Acquisition of an electron microscope for high-resolution single particle cryo-EM, Molecular Mechanisms of Iron Homeostasis, Discovering the mechanism of GPCR-mediated arrestin stimulation to enable effective drug therapies, Novel Long Acting rhTSH Superagonist Analogs for Improved Diagnostic Imaging, Thyroglobulin Stimulation and Therapy of Thyroid Cancer., Linux cluster for near atomic resolution single particle cryo-EM, Advancing cryo-EM technology to address difficult biological questions, Cancer Center Support Grant (CCSG), The Discovery of Human Peptide Encoding Genes

OpenAlex ID: W4290673782

FWCI: 4.078

Cites: 81

Cited by: 55

Related to: 10