Nanobiotics against antimicrobial resistance: harnessing the power of nanoscale materials and technologies
Year: 2022
Type: article
Abstract: Given the spasmodic increment in antimicrobial resistance (AMR), world is on the verge of "post-antibiotic era". It is anticipated that current SARS-CoV2 pandemic would worsen the situation in future, mainly due to the lack of new/next generation of antimicrobials. In this context, nanoscale materials with antimicrobial potential have a great promise to treat deadly pathogens. These functional materials are uniquely positioned to effectively interfere with the bacterial systems and augment biofilm penetration. Most importantly, the core substance, surface chemistry, shape, and size of nanomaterials define their efficacy while avoiding the development of AMR. Here, we review the mechanisms of AMR and emerging applications of nanoscale functional materials as an excellent substitute for conventional antibiotics. We discuss the potential, promises, challenges and prospects of nanobiotics to combat AMR.
Source: Journal of Nanobiotechnology
Institutions: University of Delhi, Institute of Genomics and Integrative Biology, Council of Scientific and Industrial Research, Academy of Scientific and Innovative Research, Chaudhary Charan Singh University, Tan Tock Seng Hospital, National Centre for Infectious Diseases, National University of Singapore, SingHealth Duke-NUS Academic Medical Centre, Singapore Eye Research Institute, Duke-NUS Medical School, National Skin Centre, Nanyang Technological University
Language: English
Subfield: Materials Chemistry
Field: Materials Science
Domain: Physical Sciences
Open Access status: gold
Estimated APC paid: $3,090
Awards: G3195385251, G976044396
OpenAlex ID: W4291162947