Guidelines of the International Headache Society for Controlled Clinical Trials in Cluster Headache
Year: 2022
Type: article
Abstract: In 1995, a committee of the International Headache Society developed and published the first edition of the Guidelines for Controlled Trials of Drugs in Cluster Headache. These have not been revised. With the emergence of new medications, neuromodulation devices and trial designs, an updated version of the International Headache Society Guidelines for Controlled Clinical Trials in Cluster Headache is warranted. Given the scarcity of evidence-based data for cluster headache therapies, the update is largely consensus-based, but takes into account lessons learned from recent trials and demands by patients. It is intended to apply to both drug and neuromodulation treatments, with specific proposals for the latter when needed. The primary objective is to propose a template for designing high quality, state-of-the-art, controlled clinical trials of acute and preventive treatments in episodic and chronic cluster headache. The recommendations should not be regarded as dogma and alternative solutions to particular methodological problems should be explored in the future and scientifically validated.
Source: Cephalalgia
Authors: Jean Schoenen, Agneta Henriette Snoer, Roemer B Brandt, Rolf Fronczek, Diana Y Wei, Chin-Sang Chung, Hans-Christoph Diener, David W Dodick, Denys Fontaine, Peter J Goadsby, Manjit Singh Matharu, Arne May, James S McGinley, Stewart J Tepper, Rigmor Højland Jensen, Michel D Ferrari, Jean Schoenen, Rigmor Jensen, Michel D Ferrari, Arne May, Hans-Christoph Diener, Peter J Goadsby, Manjit S Matharu, Stewart J Tepper, David W Dodick, Chin-Sang Chung, Denys Fontaine, James S McGinley, Agneta Henriette Snoer, Rolf Fronczek, Roemer W Brandt, Diana Y Wei, Gisela Terwindt, Cristina Tassorelli, Hans-Christoph Diener, Messoud Ashina, Peter J Goadsby, Elizabeth Leroux, Richard B Lipton, Patricia Pozo-Rosich, Shuu-Jiun Wang, Marie Deen Christensen, Daniela Martini, Thomas van den Hoek
Institutions: Centre Hospitalier Universitaire de Liège, Centre hospitalier régional de la Citadelle, Glostrup Hospital, Leiden University Medical Center, King's College London, Samsung Medical Center, Sungkyunkwan University, Essen University Hospital, University of Duisburg-Essen, Mayo Clinic, Mayo Clinic in Arizona, Centre Hospitalier Universitaire de Nice, UCL Queen Square Institute of Neurology, University College London, University Medical Center Hamburg-Eppendorf, Dartmouth–Hitchcock Medical Center
Language: English
Subfield: Psychiatry and Mental health
Field: Medicine
Domain: Health Sciences
Open Access status: green
Funders: U.S. Department of Defense, Amgen, Eli Lilly and Company, Pfizer, GlaxoSmithKline, Sanofi, Patient-Centered Outcomes Research Institute, Teva Pharmaceutical Industries, Celgene, Boston Scientific Corporation, Massachusetts Medical Society, University of Cambridge, University of Oxford, European Commission, Deutsche Forschungsgemeinschaft, Bundesministerium für Bildung und Forschung, Lundbeckfonden, Rigshospitalet, TrygFonden, H. Lundbeck A/S, Ipsen, National Institutes of Health, Allergan
OpenAlex ID: W4292202439