Work

MraZ Transcriptionally Controls the Critical Level of FtsL Required for Focusing Z-Rings and Kickstarting Septation in Bacillus subtilis

Year: 2022

Type: article

Abstract: alone was sufficient to abolish MraZ-mediated cell division inhibition. Using time-lapse microscopy, we showed that under conditions where the FtsL level is depleted, the cell division machinery is unable to initiate cytokinesis. Thus, our results pinpoint that the precise role of FtsL is in concentrating septal cell wall synthesis to facilitate cell division.

Source: Journal of Bacteriology

DOI: 10.1128/jb.00243-22

Authors: Maria L. White, Abigail Hough-Neidig, Sebastian J. Khan, Prahathees J. Eswara

Institution: University of South Florida

Language: English

Topic: Bacterial Genetics and Biotechnology

Subfield: Genetics

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: green

Funder: National Institute of General Medical Sciences

Award: Division site determination in Gram-positive bacteria