Role of Insulin in Cognitive Functions of the Central Nervous System
Year: 2013
Type: article
Abstract: It was previously believed that insulin only has environmental performance and is not capable of crossing the blood-brain barrier or affecting the central nervous system. However, it is now clear that insulin and its receptors are present in the central nervous system. This hormone not only passes the blood-brain barrier, but may also be synthesized by neurons in the brain. As a neuropeptide, insulin is involved in the development and function of the nervous system. Deficiency of this hormone or dysfunction of its central receptors causes serious damage to cognitive processes including learning and memory. Such effects might be due to the non-metabolic effects of insulin. This study reviewed the role of insulin in neuronal processes.
Authors: Saeideh Davari, Parham Reisi
Institution: Isfahan University of Medical Sciences
Language: English
Subfield: Endocrine and Autonomic Systems
Field: Neuroscience
Domain: Life Sciences
Open Access status: green
OpenAlex ID: W4292671972