Work

Design and exploration of gut-restricted bifunctional molecule with TGR5 agonistic and DPP4 inhibitory effects for treating ulcerative colitis

Year: 2022

Type: article

Source: European Journal of Medicinal Chemistry

DOI: 10.1016/j.ejmech.2022.114697

Authors: Fanghui Han, Mengmeng Ning, Kai Wang, Yipei Gu, Hui Qu, Ying Leng, Jianhua Shen

Institutions: Chinese Academy of Sciences, Shanghai Institute of Materia Medica, University of Chinese Academy of Sciences, State Key Laboratory of Drug Research

Language: English

Topic: Inflammatory Bowel Disease

Subfield: Genetics

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

Funders: National Natural Science Foundation of China, Science and Technology Commission of Shanghai Municipality, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences

Awards: G2958897338, G5521265569, G886082987

OpenAlex ID: W4293070774

FWCI: 0.942

Cites: 41

Cited by: 7

Related to: 10