Work

IDH1-mutant, alternative lengthening of telomeres (ALT)-dependent gliomas use the deubiquitinase BRCC3 to degrade cytosolic cGAS and avoid cGAS-STING-mediated activation of innate immunity

Year: 2022

Type: conference-abstract

Source: WFNOS 2022 Abstract Book

DOI: 10.14791/btrt.2022.10.f-2563

Authors: Joydeep Mukherjee, Yongjian Tang, Yukinori Tereda, Tor-Christian Johanessen Johanessen, Ajay Pandita, Shigeo Ohba, Daniel Cahill, Russell Pieper

Institutions: University of California, San Francisco, Harvard University, Massachusetts General Hospital

Language: English

Topic: Glioma Diagnosis and Treatment

Subfield: Genetics

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: hybrid

OpenAlex ID: W4293204073

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Related to: 10