The Efficacy and Safety of a Bacillus Probiotic Combination for the Treatment of Acute Diarrhea in Children: A Double-blind, Randomized, Placebo-controlled Multicentric Study
Year: 2022
Type: article
Study design: Clinical Trial
Abstract: prevention and treatment of gastroenteritis in several randomized controlled trials and meta-analyses.7 There have been reports that regular consumption of products containing probiotics will strengthen the body's immune system, produce an anti-allergy effect, reduces the risk for certain cancers, IntroductIonDiarrhea is defined as the passage of three or more loose or liquid stools/day (or more frequent passage than is normal for the individual).1 There is either an increase in the frequency or a decrease in the consistency of the bowel movements.Diarrhea affects people of all ages.Diarrhea is considered as a sign of an infection in the intestines, which is caused by bacteria, viruses, and parasites.In developing countries, diarrhea is considered as the second leading cause of mortality and morbidity in children.In a global scenario, it is estimated that in children below 5 years of age, there are 2.5 billion episodes of diarrhea and almost 1.5 million deaths annually due to diarrhea.2 Viruses, bacteria, and parasites are the most common infectious causes of acute diarrhea.Medication adverse effects, acute abdominal processes, gastroenterological disease, and endocrine disease are all examples of noninfectious causes.3 Diarrhea is one of the most commonly reported adverse reactions to antibacterial medications.4 AAD is observed in almost 5-30% of patients undergoing antibiotic therapy in the initial phase or even up to 2 months after the treatment is over.In pediatric populations, probiotics have been thoroughly researched in the past and are still continued to date for the prevention and, to a greater extent, in the treatment of several diarrheal diseases.6 Probiotics are known to be effective in the
Source: Pediatric Infectious Disease
Language: English
Subfield: Food Science
Domain: Life Sciences
Open Access status: diamond
OpenAlex ID: W4294031763