Work

Author response: STAG2 promotes the myelination transcriptional program in oligodendrocytes

Year: 2022

Type: peer-review

Abstract: Brain-specific inactivation of cohesin-STAG2 in the mouse causes myelination defects, thus implicating hypomyelination as a contributing factor to cohesinopathy and establishing oligodendrocytes as a cell system to probe the physiological function of cohesin-mediated genome folding.

DOI: 10.7554/elife.77848.sa2

Authors: Ningyan Cheng, Guanchen Li, Mohammed Kanchwala, Bret M Evers, Chao Xing, Hongtao Yu

Institutions: The University of Texas Southwestern Medical Center, Westlake University

Language: English

Topic: Neurogenesis and neuroplasticity mechanisms

Subfield: Developmental Neuroscience

Field: Neuroscience

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: gold

OpenAlex ID: W4294043409

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