Work

HIV-1 protease with 10 lopinavir and darunavir resistance mutations exhibits altered inhibition, structural rearrangements and extreme dynamics

Year: 2022

Type: article

Source: Journal of Molecular Graphics and Modelling

DOI: 10.1016/j.jmgm.2022.108315

Authors: Andres Wong-Sam, Yuan-Fang Wang, Daniel W. Kneller, Andrey Y. Kovalevsky, Arun K. Ghosh, Robert W. Harrison, Irene T. Weber

Institutions: Georgia State University, Oak Ridge National Laboratory, Purdue University West Lafayette

Language: English

Topic: HIV/AIDS drug development and treatment

Subfield: Infectious Diseases

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: bronze

Funders: U.S. Department of Energy, Georgia State University, National Institutes of Health, Office of Science, National Institute of Allergy and Infectious Diseases, Basic Energy Sciences, Argonne National Laboratory

Awards: G1756342139, G18202666, G1940553382, G2123841078, G4403659332, G572720644, G6125461273, Inhibition of Resistant Variants of HIV Protease, Design & Synthesis of Nonpeptide Protease Inhibitors, G9000026535, G9000236180, Design & Synthesis of Nonpeptide Protease Inhibitors

OpenAlex ID: W4294043943

FWCI: 0.488

Cites: 78

Cited by: 6

Related to: 10