Work

Hypertension Management in Patients with Chronic Kidney Disease

Year: 2022

Type: review

Abstract: Hypertension and chronic kidney disease are closely linked. Patients with chronic kidney disease have hypertension almost universally and uncontrolled hypertension accelerates the decline in kidney function. The pathophysiology of hypertension in chronic kidney disease is complex, but is largely related to reduced nephron mass, sympathetic nervous system overactivation, involvement of the renin-angiotensin-aldosterone system, and generalized endothelial dysfunction. Consensus guidelines for blood pressure targets have adopted a blood pressure <120/80 mm Hg in native chronic kidney disease and <130/80 mm Hg in kidney transplant recipients. Guidelines also strongly advocate for renin-angiotensin-aldosterone system blockade as the first-line therapy.

Source: Methodist DeBakey Cardiovascular Journal

DOI: 10.14797/mdcvj.1119

Authors: Sean A. Hebert, Hassan N. Ibrahim

Institution: The University of Texas Health Science Center at Houston

Language: English

Topic: Blood Pressure and Hypertension Studies

Subfield: Cardiology and Cardiovascular Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W4294732482

FWCI: 1.462

Cites: 69

Cited by: 33

Related to: 10