Adverse karyotype subcategories in acute myeloid leukemia display significant differences in mutation composition and transplant-augmented survival
Year: 2022
Type: article
Study design: Observational Study
Abstract: Table 1.Presenting clinical and laboratory characteristics of 189 acute myeloid leukemia (AML) patients with European LeukemiaNet adverse karyotype; a separate cohort of 325 AML patients with normal karyotype is included as a reference; rare adverse variants included inv(3)/t(3;3);i(17) and 17(p) abnormalities.P value provided is for comparisons among adverse karyotype categories.CR/Cri: complete remission with incomplete hematologic recovery.
Source: Haematologica
Authors: Ayalew Tefferi, Amritpal Singh, Naseema Gangat, Aref Al-Kali, Hassan Alkhateeb, Mithun Shah, Mrinal S. Patnaik, Michelle A. Elliott, William J. Hogan, Mark R. Litzow, Alexandra Wolanskyj-Spinner, Christopher C. Hook, Abhishek Mangaonkar, David Viswanatha, Dong Chen, Animesh Pardanani, Kebede H. Begna, Rhett P. Ketterling
Institution: Mayo Clinic
Language: English
Subfield: Hematology
Field: Medicine
Domain: Health Sciences
Open Access status: gold
Estimated APC paid: $2,157
OpenAlex ID: W4294990737