Work

Isoquinolone derivatives as lysophosphatidic acid receptor 5 (LPA5) antagonists: Investigation of structure-activity relationships, ADME properties and analgesic effects

Year: 2022

Type: article

Source: European Journal of Medicinal Chemistry

DOI: 10.1016/j.ejmech.2022.114741

Authors: Dehui Zhang, Ann M. Decker, Kristen Woodhouse, Rodney Snyder, Purvi Patel, Danni L. Harris, Yuan-Xiang Tao, Jun-Xu Li, Yanan Zhang

Institutions: RTI International, University at Buffalo, State University of New York, Rutgers, The State University of New Jersey, Rutgers New Jersey Medical School

Language: English

Topic: Sphingolipid Metabolism and Signaling

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: bronze

Funders: Research Triangle Institute, National Institutes of Health, National Institute of Mental Health, National Institute on Drug Abuse

Awards: G2378368571, Allosteric Modulation of the CB1 Receptor

OpenAlex ID: W4295419376

FWCI: 0.816

Cites: 47

Cited by: 12

Related to: 10