Work

Error-prone repair of stalled replication forks drives mutagenesis and loss of heterozygosity in haploinsufficient BRCA1 cells

Year: 2022

Type: article

Source: Molecular Cell

DOI: 10.1016/j.molcel.2022.08.017

Authors: Madhura Deshpande, Theodore Paniza, Nahed Jalloul, Gouri Nanjangud, Jerzy Twarowski, Amnon Koren, Nikica Zaninovic, Qiansheng Zhan, Kalyani Chadalavada, Anna Malkova, Hossein Khiabanian, Advaitha Madireddy, Zev Rosenwaks, Jeannine Gerhardt

Institutions: Weill Cornell Medicine, Rutgers, The State University of New Jersey, Rutgers Cancer Institute, University of Iowa, Cornell University

Language: English

Topic: DNA Repair Mechanisms

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: bronze

Funders: National Institutes of Health, National Heart, Lung, and Blood Institute, National Cancer Institute, National Institute of General Medical Sciences

Awards: The multifaceted role of the Fanconi anemia tumor suppressor pathway in facilitating DNA replication, G287242054, Personal mutational landscapes encoded in our DNA, Cancer Center Support Grant, Cancer Center Support Grant

OpenAlex ID: W4295760887

FWCI: 2.123

Cites: 69

Cited by: 29

Related to: 10