Year: 2022
Type: article
Study design: Observational Study
Abstract: This study described and compared physical activity (PA) characteristics at the end of the human lifespan using conventional cut-point-based versus cut-point-free accelerometer metrics. Eighteen institutionalized centenarians (101.5 ± 2.1 years, 72.2% female, 89% frail) wore the wrist GENEActiv accelerometer for 7 days. Conventional metrics, such as time spent in light-intensity PA (LiPA) and moderate-to-vigorous intensity PA (MVPA) were calculated according to published cut-points for adults and older adults. The following cut-point-free metrics were evaluated: average acceleration, intensity gradient and Mx metrics. Depending on the cut-point, centenarians accumulated a median of 15–132 min/day of LiPA and 3–15 min/day of MVPA. The average acceleration was 9.2 mg [Q1: 6.7 mg–Q3: 12.6 mg] and the intensity gradient was −3.19 [−3.34–−3.12]. The distribution of Z-values revealed positive skew for MVPA, indicating a potential floor effect, whereas the skew magnitude was attenuated for cut-point-free metrics such as intensity gradient or M5. However, both cut-point-based and cut-point-free metrics were similarly positively associated with functional independence, cognitive and physical capacities. This is the first time that PA has been described in centenarians using cut-point-free metrics. Our results suggest that new analytical approaches could overcome cut-point limitations when studying the oldest-old. Future studies using these new cut-point-free PA metrics are warranted to provide more complete and comparable information across groups and populations.
Institutions: Universidad de Zaragoza, Biomedical Research Networking Center in Bioengineering, Biomaterials and Nanomedicine, Centro de Investigación Biomédica en Red, Instituto de Investigación Sanitaria Aragón, Instituto de Investigación en Ingeniería de Aragón, Spanish Biomedical Research Centre in Physiopathology of Obesity and Nutrition, Centro de Investigación y Tecnología Agroalimentaria de Aragón
Language: English
Topic: Physical Activity and Health
Subfield: Physiology
Field: Medicine
Domain: Health Sciences
Open Access status: gold
Estimated APC paid: $2,618
Funders: Ministerio de Educación, Cultura y Deporte, Ministerio de Economía y Competitividad, Ministerio de Ciencia e Innovación, Universidad de Zaragoza, Gobierno de Aragón, Ministerio de Asuntos Económicos y Transformación Digital, Gobierno de España, European Research Council, European Regional Development Fund
Awards: G1000698283, G1106365238, G11116616, G1360789243, G140149096, G1674138295, G171530581, G1888088267, G2126338877, G2538236775, G2643277059, G2651803789, G2882534798, G2910395704, G329720804, G3307259962, G3372976588, G3455429901, G3570345685, G3576121327, G3680359515, G3690828678, G4139190531, G4323146741, G433486840, G4357023009, G4890552566, G507807347, G5233251722, G5263279719, G5310503911, G5334077703, G5410374029, G5440227535, G5554367290, G5596074427, G6099822883, G610064109, G6106705483, G6240230012, G6285544722, G6358633319, G6606534181, G6646709805, G6676243965, G6696268652, G673842725, G686332224, G7201015403, G7269341960, BSICoS, G7355969309, G7655004931, G822888630, G8570394447, G8610554206, G8687786062, G8776100923, G8814471684, G883467944, G90819269
OpenAlex ID: W4296002827