Changes in HIV care continuum indicators among community-based samples of HIV-infected people who inject drugs and men who have sex with men across 21 cities in India
Year: 2022
Type: article
Study design: Observational Study
Abstract: Monitoring key populations’ progress towards UNAIDS 90-90-90 targets is essential to achieving HIV/AIDS epidemic control. Using serial cross-sectional data, we evaluated changes in HIV care continuum among people who inject drugs(PWID) and men who have sex with men(MSM) in India. Cross-sectional baseline (2012/2013) and follow-up (2016/2017) samples were recruited using respondent-driven sampling across 21 cities. All participants were tested for HIV and RNA measured in HIV-positive participants. Linear regression was used to model temporal site-level changes in continuum indicators in MSM versus PWID. At baseline, we recruited 2,544 HIV-infected PWID and 1,086 HIV-infected MSM. At follow-up, we recruited 2,517 HIV-infected PWID and 1,763 HIV-infected MSM. At baseline, there were no significant differences in continuum indicators between MSM and PWID. At follow-up, compared to PWID, the proportion of MSM reaching each care continuum indicator—awareness of status, receipt of care, ART use, viral suppression—increased by 15-33 percentage points: 78% of MSM versus 49% of PWID were aware of their status (p < 0.01); 56% of MSM versus 32% of PWID were virologically suppressed (p = 0.05). MSM showed marked improvements across the care continuum, whereas PWID lagged and may require additional intervention. Differential improvement in HIV engagement may necessitate population-specific interventions and routine surveillance to facilitate HIV elimination.
Source: AIDS Care
Language: English
Subfield: Infectious Diseases
Field: Medicine
Domain: Health Sciences
Open Access status: green
Funders: Division of Intramural Research, National Institute of Allergy and Infectious Diseases, Johns Hopkins University, Elton John AIDS Foundation, National Institutes of Health, Center for AIDS Research, University of Washington, Center for AIDS Research, Johns Hopkins University, National Institute of Mental Health, National Institute on Drug Abuse, National Institute of Allergy and Infectious Diseases, NHLBI Division of Intramural Research
Awards: G1230754110, Preventing HIV Infection Among MSM in Southern India, Investigating the Potential of Respondent-Driven Sampling to Reach Undiagnosed, Out-of-Care HIV-infected People Who Inject Drugs, G2483435703, Integrated Care Clinics for IDUs in India: a cluster randomized trial, Strategies to improve the HIV care continuum among key populations in India, G7178514535, G7975956611, Treatment outcomes and comorbidity in HIV-infected IDU, The Johns Hopkins Center for AIDS Research (JHU CFAR), Traineeships in AIDS Prevention Studies, Johns Hopkins HIV Epidemiology and Prevention Sciences Training Program
OpenAlex ID: W4296191249