Previtamin D action spectrum: Challenging CIE towards a standard
Year: 2022
Type: article
Abstract: In 2006, CIE published a technical report on an action spectrum for the production of previtamin D 3 in human skin. CIE procedure is to publish guidelines (e.g., an action spectrum) and let the community test them before moving to define a standard. The CIE previtamin D 3 action spectrum has been in use for 15 years, and challenged on several occasions; a number of alternative action spectra have been suggested. To date (2021) no alternative action spectrum has shown clear advantages over the CIE version when tested against experimental outcomes. Thus, the CIE action spectrum remains widely used, but not fully accepted as best representing the photobiology in human skin leading to synthesis of vitamin D. We report on a CIE workshop designed to address the challenges to the CIE action spectrum, and explore alternative action spectra. The workshop concluded that the CIE action spectrum probably requires amendment, with several candidates for consideration in determining any changes. However, until there is a clear alternative, the CIE action spectrum should remain in use whilst ensuring full spectral information about sources of ultraviolet radiation. Thus, results are comparable between studies and can be recalculated to an updated action spectrum if necessary.
Source: Lighting Research & Technology
Institutions: University of Manchester, National Academy of Sciences of Ukraine, Institute of Physics, Boston University, Boston Medical Center, National Institute for Public Health and the Environment, National Institute of Water and Atmospheric Research, Australian National University, King's College London, Copenhagen University Hospital, Leiden University Medical Center
Language: English
Topic: Vitamin D Research Studies
Subfield: Pathology and Forensic Medicine
Field: Medicine
Domain: Health Sciences
Open Access status: hybrid
Estimated APC paid: $3,750
OpenAlex ID: W4296448355