Work

Current trends in diagnosis and management of follicular lymphoma.

Year: 2022

Type: review

Abstract: Follicular lymphoma (FL) originates from germinal center B cells, is the most prevalent form of indolent non-Hodgkin's lymphoma. Upfront management is based on stage, grade, and disease burden. Radiotherapy may be curative in limited disease while chemoimmunotherapy is preferred in advanced disease. Maintenance therapy is routinely administered but its role is debatable. Relapses are common and interval from initial therapy to relapse is most important prognostic factor for relapsed FL. Management of relapsed patients is based on the initial management, the interval from prior therapies, and the toxicity of available therapies. Multiple agents are available for patients after two or more lines of therapy, but sequencing remains poorly defined.

Source: PubMed

Authors: Gopila Gupta, Vikas Garg, Saumyaranjan Mallick, Ajay Gogia

Institutions: Fortis Healthcare, DR. B.R.A. Institute Rotary Cancer Hospital, All India Institute of Medical Sciences

Language: English

Topic: Lymphoma Diagnosis and Treatment

Subfield: Pathology and Forensic Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W4296802329

FWCI: 0.472

Cites: 109

Cited by: 15

Related to: 10