Work

Delirium and Cortical Complexity: Divergent Changes in Alpha and Theta Bands

Year: 2022

Type: article

Abstract: We thank Dr. Kim and colleagues for their interest in our paper (1) and their thought-provoking parallel analyses of their data (2). Although it would have been interesting to see a broadband calculation of Lempel–Ziv complexity (LZC) as we had originally published, the findings of divergent changes in alpha and theta band LZC with delirium are intriguing. Therefore, we have conducted similar analyses of our published data, replicating the findings of Dr. Kim and colleagues for the theta and alpha band, but not the high alpha band. The EEG data are derived from a perioperative cohort study of adult patients undergoing thoracic aortic aneurysm repair (IPOD-B2) and the cohort of adult patients (>65 years old) undergoing major surgery (IPOD-B3). After excluding patient data with severe artifacts, 89 patients were diagnosed for delirium status depending on the postoperative confusion assessment method (CAM+/- or CAM-ICU+/- if ventilated) and...

Source: The Journals of Gerontology Series A

DOI: 10.1093/gerona/glac165

Authors: Sean Tanabe, Maggie Parker, Richard Lennertz, Robert A Pearce, Matthew I Banks, Robert D Sanders

Institutions: University of Michigan, University of Wisconsin–Madison, The University of Sydney, Royal Prince Alfred Hospital

Language: English

Topic: Intensive Care Unit Cognitive Disorders

Subfield: Critical Care and Intensive Care Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

Funder: National Institute on Aging