Work

Realtime Photoacoustic Microscopy of Murine Cardiovascular Dynamics

Year: 2008

Type: article

Abstract: Non-invasive visualization of cardiovascular dynamics in small animals is challenging due to their rapid heart-rates. We present a realtime photoacoustic imaging system consisting of a 30-MHz ultrasound array transducer, receive electronics, a high-repetition-rate laser, and a multicore-computer, and demonstrate its ability to image optically-absorbing structures of the beating hearts of young athymic nude mice at rates of ~50 frames per second with 100 µm×25 µm spatial resolution. To our knowledge this is the first report of realtime photoacoustic imaging of physiological dynamics.

Source: Optics Express

DOI: 10.1364/oe.16.018551

Authors: R.J. Zemp, L. Song, R. Bitton, K.K. Shung, L.V. Wang

Institutions: University of Alberta, Washington University in St. Louis, University of Southern California

Language: English

Topic: Photoacoustic and Ultrasonic Imaging

Subfield: Biomedical Engineering

Field: Engineering

Domain: Physical Sciences

Open Access status: gold

Estimated APC paid: $2,270

Funders: National Institutes of Health, National Institute of Biomedical Imaging and Bioengineering