Work

Phase I/II study of azacitidine and capecitabine/oxaliplatin (CAPOX) in refractory CIMP-high metastatic colorectal cancer: evaluation of circulating methylated vimentin

Year: 2020

Type: article

Abstract: Hypermethylation of promoter CpG islands (CIMP) has been strongly implicated in chemotherapy resistance and is implicated in the pathogenesis of a subset of colorectal cancers (CRCs) termed CIMP-high.

Source: Carolina Digital Repository (University of North Carolina at Chapel Hill)

DOI: 10.17615/kke1-de47

Authors: Feng, Tian, LaFramboise, Thomas, Lee, Michael S., Eng, Cathy, Fogelman, David, Hamilton, Stanley, Kopetz, Scott, Markowitz, Sanford D., Moinova, Helen, Shroff, Rachna T., Mazard, Thibault, Overman, Michael J., Morris, Van, Broom, Bradley, Issa, Jean-Pierre, Manyam, Ganiraju, Kee, Bryan, Ensor, Joe, Lutterbaugh, James

Institution: University of North Carolina at Chapel Hill

Language: English

Topic: Colorectal Cancer Treatments and Studies

Subfield: Oncology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

Funders: Celgene, National Institutes of Health

Awards: G9000034222, G9000084944

OpenAlex ID: W4297940563

FWCI:

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