Genome-wide linkage analysis of 1,233 prostate cancer pedigrees from the International Consortium for prostate cancer Genetics using novel sumLINK and sumLOD analyses
Year: 2020
Type: article
Study design: Observational Study
Abstract: Prostate cancer is generally believed to have a strong inherited component, but the search for susceptibility genes has been hindered by the effects of genetic heterogeneity. The recently developed sumLINK and sumLOD statistics are powerful tools for linkage analysis in the presence of heterogeneity.
DOI: 10.17615/cv63-ck59
Authors: Hsieh, Chih-Lin, Oakley-Girvan, Ingrid, Easton, Douglas, Severi, Gianluca, Thibodeau, Stephen N., Whittemore, Alice S., Eeles, Ros, Powell, Isaac, Moller, Pal, Giles, Graham G., Foulkes, William D., McIntosh, Laura, Bailey-Wilson, Joan E., Hopper, John L., Deutsch, Kerry, Isaacs, Sarah D., Dimitrov, Latchezar, Isaacs, William B., Johanneson, Bo, Walsh, Patrick C., English, Dallas R., Wiley, Kathleen E., Christensen, G. Bryce, Xu, Jianfeng, Maehle, Lovise, McDonnell, Shannon K., Stanford, Janet L., Baffoe-Bonnie, Agnes B., George, Asha, Badzioch, Michael D., Carpten, John D., Ostrander, Elaine A.
Language: English
Subfield: Genetics
Domain: Life Sciences
Open Access status: green
Funders: U.S. Department of Defense, Fred Hutchinson Cancer Research Center, Utah State University, University of Utah, Huntsman Cancer Institute, Cancerfonden, Tampereen Yliopisto, Umeå Universitet, Deutsche Krebshilfe, Universität Ulm, Pirkanmaan Sairaanhoitopiiri, National Institutes of Health, U.S. Public Health Service, Medical Research Council, National Health and Medical Research Council, Cancer Council Victoria, National Human Genome Research Institute, National Cancer Institute, U.S. National Library of Medicine, National Center for Research Resources, National Institute on Minority Health and Health Disparities
Awards: G1557257169, The causes of prostate cancer, G2768455175, G284809622, G3729156826, G3854076888, What is the risk of prostate cancer over 5, 10 and 20 years for a man with a specific set of risk factors?, G5272917877, G6191607766, G6455403188, PLATYPUSES, Epidemiology of Chronic Disease, Health Interventions and DNA Studies, G7136903082, G7400227903, G7780735200, G8123808567, G8235188447, G9000027172, G9000036580, G9000130915, G9000182601, G9000311831, G9000327744, G921727105
OpenAlex ID: W4297950061