The complete genome sequence of Staphylothermus marinus reveals differences in sulfur metabolism among heterotrophic Crenarchaeota
Year: 2008
Type: article
Abstract: Background: Staphylothermus marinus is an anaerobic, sulfur-reducing peptide fermenter of the archaeal phylum Crenarchaeota.It is the third heterotrophic, obligate sulfur reducing crenarchaeote to be sequenced and provides an opportunity for comparative analysis of the three genomes.Results: The 1.57 Mbp genome of the hyperthermophilic crenarchaeote Staphylothermus marinus has been completely sequenced.The main energy generating pathways likely involve 2-oxoacid:ferredoxin oxidoreductases and ADP-forming acetyl-CoA synthases.S. marinus possesses several enzymes not present in other crenarchaeotes including a sodium ion-translocating decarboxylase likely to be involved in amino acid degradation.S. marinus lacks sulfur-reducing enzymes present in the other two sulfur-reducing crenarchaeotes that have been sequenced -Thermofilum pendens and Hyperthermus butylicus.Instead it has three operons similar to the mbh and mbx operons of Pyrococcus furiosus, which may play a role in sulfur reduction and/or hydrogen production.The two marine organisms, S. marinus and H. butylicus, possess more sodium-dependent transporters than T. pendens and use symporters for potassium uptake while T. pendens uses an ATP-dependent potassium transporter.T. pendens has adapted to a nutrient-rich environment while H. butylicus is adapted to a nutrient-poor environment, and S. marinus lies between these two extremes. Conclusions:The three heterotrophic sulfur-reducing crenarchaeotes have adapted to their habitats, terrestrial vs. marine, via their transporter content, and they have also
Authors: Anderson, Iain J., Dharmarajan, Lakshmi, Rodriguez, Jason, Hooper, Sean, Porat, Iris, Ulrich, Luke E., Elkins, James G., Mavromatis, Kostas, Sun, Hui, Land, Miriam, Lapidus, Alla, Lucas, Susan, Barry, Kerrie, Huber, Harald, Zhulin, Igor B., Whitman, William B., Mukhopadhyay, Biswarup, Woese, Carl, Bristow, James, Kyrpides, Nikos
Language: English
Subfield: Molecular Biology
Domain: Life Sciences
Open Access status: green
Funders: U.S. Department of Energy, National Aeronautics and Space Administration, National Institutes of Health, National Institute of General Medical Sciences, Biological and Environmental Research, Lawrence Livermore National Laboratory, Lawrence Berkeley National Laboratory, Los Alamos National Laboratory
Awards: G1079818582, G1143651532, G1286236842, G1337544421, G1356433355, G1632040200, G1716777315, G2145270357, G222768804, G223002938, G2596126017, G2640090911, G2717806384, G2812390658, G2988778103, G3083819904, G3571461640, G3669113783, G382641700, Computational Genomics of Signal Transduction, G5738753633, A NOVEL COENZYME F420-DEPENDENT SUFITE REDUCTASE, G6676218673, G7354628648, BIOCHEMISTRY AND GENETICS OF AUTOTROPY IN METHANOCCUS, G7787287669, G8326222658, G8437677540, G8527315880, G895790057, G969889393, G991281326
OpenAlex ID: W4298019643