Genomic Variation Associated With Mortality Among Adults of European and African Ancestry With Heart Failure: The Cohorts for Heart and Aging Research in Genomic Epidemiology Consortium
Year: 2020
Type: article
Study design: Observational Study
Abstract: Prognosis and survival are significant concerns for individuals with heart failure (HF). In order to better understand the pathophysiology of HF prognosis, the association between 2,366,858 single nucleotide polymorphisms (SNPs) and all-cause mortality was evaluated among individuals with incident HF from four community-based prospective cohorts: the Atherosclerosis Risk in Communities Study, the Cardiovascular Health Study, the Framingham Heart Study, and the Rotterdam Study.
DOI: 10.17615/4tec-rx52
Authors: Bis, Joshua C., Wang, Ying A., Cupples, L. Adrienne, Chang, Patricia P., Willerson, James T., Boerwinkle, Eric, Glazer, Nicole L., Benjamin, Emelia J., Rice, Kenneth M., Fox, Ervin R., Witteman, Jacqueline C.M., Morrison, Alanna C., Smith, Nicholas L., Haritunians, Talin, Stricker, Bruno H., Uitterlinden, Andre G., Psaty, Bruce M., Dehghan, Abbas, Lumley, Thomas, Loehr, Laura R., O'Donnell, Christopher J., Rosamond, Wayne D., Levy, Daniel, Folsom, Aaron R., Aulchenko, Yurii S., Rivadeneira, Fernando, Felix, Janine F., Vasan, Ramachandran S., Couper, David, Rotter, Jerome I., Wang, Thomas J., Hofman, Albert, Demissie, Serkalem, Van Duijn, Cornelia M.
Institution: University of North Carolina at Chapel Hill
Language: English
Subfield: Genetics
Domain: Life Sciences
Open Access status: green
Funders: Cedars-Sinai Medical Center, European Commission, ZonMw, Erasmus Universiteit Rotterdam, Hartstichting, Erasmus Medisch Centrum, Nederlandse Organisatie voor Wetenschappelijk Onderzoek, National Institutes of Health, National Heart, Lung, and Blood Institute, National Institute of Diabetes and Digestive and Kidney Diseases, National Center for Research Resources
Awards: G1028935811, G118440752, G136105103, G1462415530, G1909643007, G215333750, G234459253, G250621538, G25881238, G277826483, G2800149121, G2818913090, G29933701, G3042145041, G36937976, G4145745212, G423252844, G445457422, G4671189754, G4824283243, G4864106686, G4932516547, G4987078009, G5125936451, G528395701, G536099884, Genome-Wide Association for Loci Influencing CHD and Other Heart, Lung and Blood, G5457026379, G5522185877, Epidemiology of Venous Thrombosis and Pulmonary Embolism, CHS Events Follow-up Study, G6204895930, G6576172577, G6860406196, G6902273418, G777822606, G786153652, G793702358, CHS-Transition Phase -268055222, G9000015747, G9000018826, G9000027259, G9000028264, G9000069887, G9000080822, G9000108254, G9000124674, G9000126117, G9000140433, G9000145448, G9000152345, G9000155493, G9000159977, G9000239991, G9000254626, G9000294005, G9000294209, From GWAS loci to blood pressure genes, variants & mechanisms - Renewal, G905887895, G960597250
OpenAlex ID: W4298191966