Preventable Patient Harm: a Multidisciplinary, Bundled Approach to Reducing Clostridium difficile Infections While Using a Glutamate Dehydrogenase/Toxin Immunochromatographic Assay/Nucleic Acid Amplification Test Diagnostic Algorithm
Year: 2018
Type: article
Abstract: detection, health care facilities are questioning how best to use highly sensitive nucleic acid amplification tests (NAATs) to aid in the diagnosis of CDI. Our institution has used a two-step glutamate dehydrogenase (GDH)/toxin immunochromatographic assay/NAAT algorithm since 2009. In 2016, our institution set an organizational goal to reduce our CDI rates by 10% by July 2017. We achieved a statistically significant reduction of 42.7% in our HO-CDI rate by forming a multidisciplinary group to implement and monitor eight key categories of infection prevention interventions over a period of 13 months. Notably, we achieved this reduction without modifying our laboratory algorithm. Significant reductions in CDI rates can be achieved without altering sensitive laboratory testing methods.
Source: Journal of Clinical Microbiology
DOI: 10.1128/jcm.00625-18
Authors: Katherine Schultz, Emily Sickbert-Bennett, Ashley Marx, David J. Weber, Lauren M. DiBiase, Stacy Campbell-Bright, Lauren E. Bode, Mike Baker, Tom Belhorn, Mark Buchanan, Sherie Goldbach, Jacci Harden, Emily Hoke, Beth Huenniger, Jonathan J. Juliano, Michael Langston, Heather Ritchie, William A. Rutala, Jason Smith, Shelley Summerlin-Long, Lisa Teal, Peter Gilligan
Language: English
Subfield: Infectious Diseases
Field: Medicine
Domain: Health Sciences
Open Access status: bronze
OpenAlex ID: W2848996530