Work

Effect of anesthesia carrier gas on in vivo circulation times of ultrasound microbubble contrast agents in rats

Year: 2020

Type: article

Abstract: Microbubble contrast agents are currently implemented in a variety of both clinical and preclinical ultrasound imaging studies. The therapeutic and diagnostic capabilities of these contrast agents are limited by their short in-vivo lifetimes, and research to lengthen their circulation times is ongoing. In this manuscript, observations are presented from a controlled experiment performed to evaluate differences in circulation times for lipid shelled perfluorocarbon-filled contrast agents circulating within rodents as a function of inhaled anesthesia carrier gas.

Source: Carolina Digital Repository (University of North Carolina at Chapel Hill)

DOI: 10.17615/fw1n-by40

Authors: Dayton, Paul A., Kwan, James, Borden, Mark A., Gessner, Ryan, Mullin, Lee, Kaya, Mehmet

Language: English

Topic: Ultrasound and Hyperthermia Applications

Subfield: Biomedical Engineering

Field: Engineering

Domain: Physical Sciences

SDG: Good health and well-being

Open Access status: green

Funders: National Institutes of Health, National Institute of Biomedical Imaging and Bioengineering

Award: Immune-Shielded, Ultrasound-Stimulated Contrast Agents for Molecular Imaging