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Oral and sublingual immunotherapy for food allergy: current progress and future directions

Year: 2020

Type: article

Abstract: Food allergies are increasing in prevalence and present an emerging epidemic for westernized countries. Strict dietary avoidance is the only approved management for food allergy, but accidental exposures regularly occur, leading to significant patient anxiety and decreased quality of life. Over the past decade, oral and sublingual immunotherapies have emerged as potential treatments for food allergy. While several small clinical trials have demonstrated that immunotherapy can desensitize food-allergic individuals, strategies for further enhancing safety and definitively establishing long-term efficacy are needed. This review presents an overview of recent oral and sublingual immunotherapy trials, and provides a glimpse into what the next generation of food immunotherapy may entail.

Source: Carolina Digital Repository (University of North Carolina at Chapel Hill)

DOI: 10.17615/vbgt-n809

Authors: Burks, A Wesley, Moran, Timothy P, Vickery, Brian P

Language: English

Topic: Food Allergy and Anaphylaxis Research

Subfield: Immunology and Allergy

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W4298274546

FWCI:

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Related to: 10