Work

Thrombin-promoted release of UDP-glucose from human astrocytoma cells: Thrombin-promoted release of UDP-glucose

Year: 2020

Type: article

Abstract: The P2Y14 receptor is activated by UDP-sugars, most potently by UDP-glucose, but not by free nucleotides, suggesting that UDP-glucose is the cognate agonist for this receptor. However, evidence for regulated release of UDP-glucose is scarce. In the present study, the occurrence of receptor-promoted release of UDP-glucose was investigated, using 1321N1 human astrocytoma cells.

Source: Carolina Digital Repository (University of North Carolina at Chapel Hill)

DOI: 10.17615/afh8-3z02

Authors: Seminario-Vidal, L., Kreda, S. M., Lazarowski, E. R., Van Heusden, C.

Institution: University of North Carolina at Chapel Hill

Language: English

Topic: Adenosine and Purinergic Signaling

Subfield: Physiology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

Funder: National Institutes of Health