Work

A genome-wide study of lipid response to fenofibrate in Caucasians: a combined analysis of the GOLDN and ACCORD studies

Year: 2020

Type: article

Abstract: Fibrates are commonly prescribed for hypertriglyceridemia but also lower low-density lipoprotein cholesterol (LDL-C) and raise high-density lipoprotein cholesterol (HDL-C). Large inter-individual variation in lipid response suggests that some persons may benefit more than others and genetic studies could help identify those persons.

Source: Carolina Digital Repository (University of North Carolina at Chapel Hill)

DOI: 10.17615/r998-ha33

Authors: Borecki, Ingrid B., Guo, Xiuqing, Marvel, Skylar, Hidalgo, Bertha, Claas, Steven A., Srinivasasainagendra, Vinodh, Aslibekyan, Stella, Motsinger-Reif, Alison, Chen, Ida Y.D., Ordovas, Jose M., Straka, Robert J., Buse, John B., Irvin, Marguerite R., Rotter, Jerome I., Arnett, Donna K., Wagner, Michael J., Zhi, Degui, Rotroff, Daniel M.

Institution: University of North Carolina at Chapel Hill

Language: English

Topic: Lipoproteins and Cardiovascular Health

Subfield: Surgery

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

Funders: National Institutes of Health, Centers for Disease Control and Prevention, National Institute on Aging, National Heart, Lung, and Blood Institute, National Eye Institute, National Institute of Diabetes and Digestive and Kidney Diseases, National Center for Advancing Translational Sciences

Awards: G1028935811, G1462415530, G1910112017, G1955785366, G2150788371, G217652925, G2791092843, UCLA Clinical and Translational Science Institute, G3692229207, G401067667, G4931486092, G77894727, G781655334

OpenAlex ID: W4298298372

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