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The HLA–DRB1 shared epitope is associated with susceptibility to rheumatoid arthritis in African Americans through European genetic admixture

Year: 2020
Type: article
Study design: Observational Study
Abstract: To determine whether shared epitope (SE)–containing HLA–DRB1 alleles are associated with rheumatoid arthritis (RA) in African Americans and whether their presence is associated with higher degrees of global (genome-wide) genetic admixture from the European population.
DOI: 10.17615/cvh4-gq95
Authors: Jonas, Beth L., Morrison, Dahliann, Parrish, Lezlie A., Mikuls, Ted R., Smith, Edwin A., Bridges, S. Louis, Dwivedi, Harshit, Padilla, Miguel A., Callahan, Leigh F., Kelley, James M., Reich, David, Hughes, Laura B., Holers, V. Michael, Patterson, Nick, Gilkeson, Gary S., Vaughan, L. Kelly, Howard, George, Westfall, Andrew O., Conn, Doyt L., Alarcón, Graciela S., Moreland, Larry W.
Language: English
Subfield: Rheumatology
Field: Medicine
Open Access status: green
Funders: Amgen, Bristol-Myers Squibb, Emory University, University of South Carolina, National Institutes of Health, Genentech, National Center for Research Resources
OpenAlex ID: W4298882569
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