Work

Polyunsaturated fatty acid interactions and breast cancer incidence: a population-based case-control study on Long Island, New York

Year: 2020

Type: article

Abstract: Experimental studies demonstrate that ω-3 polyunsaturated fatty acids (PUFAs) inhibit inflammatory eicosanoids generated by ω-6 PUFAs. Epidemiologic studies on dietary ω-3 PUFA intake show consistent inverse associations with breast cancer incidence among Asian populations, where ω-3, relative to ω-6, intake is high. In contrast, associations are inconsistent among Western populations, where intake of ω-3, relative to ω-6, intake is low. We hypothesized that examining interactions between ω-3 and ω-6 would help elucidate the PUFA-breast cancer association in the U.S.

Source: Carolina Digital Repository (University of North Carolina at Chapel Hill)

DOI: 10.17615/te66-9x52

Authors: Shen, Jing, Terry, Mary Beth, Neugut, Alfred I., Ahsan, Habibul, Bradshaw, Patrick T., Steck, Susan E., He, Ka, Khankari, Nikhil K., Chen, Yu, Gammon, Marilie D., Ahn, Jiyoung, Santella, Regina M., Olshan, Andrew F., Teitelbaum, Susan L.

Language: English

Topic: Fatty Acid Research and Health

Subfield: Nutrition and Dietetics

Field: Nursing

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W4299512382

FWCI:

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