Work

Reengineering a receptor footprint of adeno-associated virus enables selective and systemic gene transfer to muscle

Year: 2009

Type: article

Source: Nature Biotechnology

DOI: 10.1038/nbt.1599

Authors: Aravind Asokan, Julia C Conway, Jana L Phillips, Chengwen Li, Julia Hegge, Rebecca Sinnott, Swati Yadav, Nina DiPrimio, Hyun-Joo Nam, Mavis Agbandje-McKenna, Scott McPhee, Jon Wolff, R Jude Samulski

Institutions: University of North Carolina at Chapel Hill, Mirus Bio (United States), University of Florida, AskBio (United States)

Language: English

Topic: Virus-based gene therapy research

Subfield: Genetics

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

Funders: American Heart Association, National Institutes of Health, National Heart, Lung, and Blood Institute, National Institute of General Medical Sciences, National Institute of Allergy and Infectious Diseases, National Institute of Arthritis and Musculoskeletal and Skin Diseases

Awards: G110866749, Rational and Combinatorial Engineering of AAV Vectors, Senator Paul D. Wellstone Muscular Dystrophy Cooperative Research Center, Muscle-specific AAV Vectors for DMD Gene Therapy, G4443903763, G6809074, AAV capsids and their cellular interactions, Determinants of AAV Tropism

OpenAlex ID: W2061013034

FWCI: 8.903

Cites: 21

Cited by: 266

Related to: 10