Work

Periostin Is a Novel Factor in Cardiac Remodeling After Experimental and Clinical Unloading of the Failing Heart

Year: 2020

Type: article

Abstract: Maladaptive left ventricular hypertrophy (LVH) remains a prevalent and highly morbid condition associated with end-stage heart disease. Originally evaluated in the context of bone development, periostin is important in endocardial cushion formation and has recently been implicated in heart failure. Because of its potential role in cardiovascular development, we sought to establish the role of periostin after relief of pressure overload in animal and human models.

Source: Carolina Digital Repository (University of North Carolina at Chapel Hill)

DOI: 10.17615/89nv-br78

Authors: Andersen, Nancy M., Selzman, Craig H., Stansfield, William E., Tang, Ru Hang

Institution: University of North Carolina at Chapel Hill

Language: English

Topic: Cardiac Fibrosis and Remodeling

Subfield: Cardiology and Cardiovascular Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

Funder: American College of Surgeons