Work

Phase I/II Trial of the Anti-HIV Activity of Mifepristone in HIV-Infected Subjects ACTG 5200

Year: 2020

Type: article

Study design: Clinical Trial

Abstract: Mifepristone is a glucocorticoid receptor inhibitor shown in vitro to have anti-HIV activity and anti-simian immunodeficiency virus activity in a macaque model. A phase I/II trial was performed to assess the drug’s safety and anti-HIV activity.

Source: Carolina Digital Repository (University of North Carolina at Chapel Hill)

DOI: 10.17615/qn0y-db22

Authors: Yu, Song, Tebas, Pablo, Para, Michael F, Rosenkranz, Susan L, Lertora, Juan, Weiner, David, Reeds, Dominic, White, C Jo, Schouten, Jeff, Cavert, Winston, Patterson, Kristine B, Daar, Eric S, Brizz, Barbara

Language: English

Topic: HIV/AIDS drug development and treatment

Subfield: Infectious Diseases

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

Funders: University of Pennsylvania, Ohio State University, University of Minnesota, University of Washington, University of Pittsburgh, Georgetown University, ACT Government, National Institute of Allergy and Infectious Diseases, National Center for Research Resources

Awards: G115468880, G1214792496, G1852790566, G2027736814, G4797509974, G674907753

OpenAlex ID: W4299722268

FWCI:

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