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Atopic asthmatic patients have reduced airway inflammatory cell recruitment after inhaled endotoxin challenge compared with healthy volunteers

Year: 2020

Type: article

Abstract: Atopic asthmatic patients are reported to be more sensitive to the effects of environmental endotoxin (LPS) than healthy volunteers (HVs). It is unknown whether this sensitivity is due to dysregulated inflammatory responses after LPS exposure in atopic asthmatic patients.

Source: Carolina Digital Repository (University of North Carolina at Chapel Hill)

DOI: 10.17615/ar8k-zm58

Authors: Brickey, Willie June, Hernandez, Michelle L., Zhou, Haibo, Peden, David B., Ting, Jenny P.Y., Herbst, Margaret, Alexis, Neil E., Lay, John C.

Institution: University of North Carolina at Chapel Hill

Language: English

Topic: Asthma and respiratory diseases

Subfield: Physiology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

Funders: U.S. Environmental Protection Agency, American Association of Immunologists, GlaxoSmithKline, Georgia Clinical and Translational Science Alliance, National Institutes of Health, National Heart, Lung, and Blood Institute, National Institute of Allergy and Infectious Diseases, National Institute of Environmental Health Sciences, National Center for Research Resources

Awards: G3259178470, UNC Clinical Translation Science Award-K12 Scholars Program (KL2), UNC Clinical and Translational Science Award, G6987138936, Immunobiology of Acute Environmental Asthma, G9000104266

OpenAlex ID: W4299736664

FWCI:

Cites:

Cited by: 2

Related to: 10