Association of Cervical Effacement With the Rate of Cervical Change in Labor Among Nulliparous Women
Year: 2016
Type: article
Abstract: OBJECTIVE: To assess the association of cervical effacement with the rate of intrapartum cervical change among nulliparous women. METHODS: We conducted a secondary analysis of a prospective trial of intrapartum fetal pulse oximetry. For women who had vaginal deliveries, interval-censored regression was used to estimate the time to dilate at 1-cm intervals. For each given centimeter of progressive cervical dilation, women were divided into those who had achieved 100% cervical effacement and those who had not. The analysis was performed separately for women in spontaneous labor and those who were given oxytocin. RESULTS: A total of 3,902 women were included in this analysis, 1,466 (38%) who underwent labor induction, 1,948 (50%) who underwent labor augmentation (combined for the analysis), and 488 (13%) who labored spontaneously. For women in spontaneous labor, the time to dilate 1 cm was shorter for those who were 100% effaced starting at 4 cm of cervical dilation (P=.01 to <.001). For women who received oxytocin, the time to dilate 1 cm was shorter for those who were 100% effaced throughout labor (P<.001). CONCLUSION: The rate of cervical dilation among nulliparous women is associated with not only the degree of cervical dilation, but also with cervical effacement. CLINICAL TRIAL REGISTRATION: ClinicalTrials.gov, www.clinicaltrials.gov, NCT00098709.
Source: Obstetrics and Gynecology
Institutions: University of North Carolina at Chapel Hill, Memorial Hermann, University of Pittsburgh, University of Utah, University of Alabama at Birmingham, The Ohio State University, Columbia University, The University of Texas Southwestern Medical Center, The University of Texas Health Science Center at Houston, Stanford University, National Institutes of Health, George Washington University, Eunice Kennedy Shriver National Institute of Child Health and Human Development
Language: English
Subfield: Obstetrics and Gynecology
Field: Medicine
Domain: Health Sciences
Open Access status: green
Awards: G1216570417, G143066087, General Clinical Research Center, Maternal Fetal Medicine Network: Data Coordinating Cent*, G1882602020, G195653943, Eunice Kennedy Shriver NICHD Maternal Fetal Medicine Units Network, Maternal Fetal Medicine Units Network, G2172336706, G2254024324, NICHD Maternal Fetal Medicine Units Network, G2594613454, G2720419288, NICHD Maternal-Fetal Medicine Units (MFMU) Network, G2797703034, G284963502, G2925552923, G29782494, G307553905, G3170774280, NICHD Maternal Fetal Medicine Units Network, G3218948901, G3685988116, Eunice Kennedy Shriver NICHD Maternal Fetal Medicine Units Network, Cooperative Multicenter Maternal Fetal Medicine Units Networks, G3786447104, G3875946430, G3955831376, G4027080872, Co-Operative Multicenter Trials in Obstetrics & Maternal Fetal Medicine, G4259014447, Data Coord Ctr-NICHD Cooperative Multicenter Maternal Medicine Units Research Net, MULTICENTER NETWORK OF MATERNAL-FETAL MEDICINE UNITS, Multicenter Network of Maternal Fetal Medicine Units, G4657398957, G4772972313, G5050941685, G50908112, G5851258965, G5864221601, G5882344285, G5987270356, G6113204387, G6233940224, Eunice Kennedy Shriver NICHD Maternal Fetal Medicine Units Network (U10), G6657596466, G673807916, Brown/WIH Eunice Kennedy Shriver NICHD MFM Units Network Site, Maternal Fetal Medicine Network, G7372122175, G7406996971, G7674919133, G7750490871, G7910209352, NICHD Materal Fetal Medicine Units Network, MULTICENTER NETWORK OF MATERNAL-FETAL MEDICINE UNITS, G8411766529, G8461220812, G8634980954, G8650048904, G8759751075, G8919699124, UofU Maternal-Fetal Medicine Units (MFMU) Network: Clinical Centers, NICHD Maternal-Fetal Medicine Units (MFMU) Network: Data CoordinatingCenter, Brown University/Women & Infants Hospital of Rhode Island (WIH) Center Application for the Eunice Kennedy Shriver NICHD Maternal Fetal Medicine Units Network, Maternal Fetal Medicine Units Network - Northwestern Study Center, Maternal-Fetal Medicine Units (MFMU) Network, Case Western Reserve University Center of the NICHD MFMU Network, Columbia University Maternal-Fetal Medicine Units Network Clinical Center, NICHD maternal fetal medicine units network, UNC MFMU: Advancing Perinatal Health via Definitive, Multi-Site Clinical Studies, Eunice Kennedy Shriver NICHD Maternal-Fetal Medicine Units (MFMU) Network (UG1), G922324195
OpenAlex ID: W2271598661