Work

Most Common SNPs Associated with Rheumatoid Arthritis in Subjects of European Ancestry Confer Risk of Rheumatoid Arthritis in African-Americans

Year: 2020

Type: article

Study design: Observational Study

Abstract: Large-scale genetic association studies have identified over 20 rheumatoid arthritis (RA) risk alleles among individuals of European ancestry. The influence of these risk alleles has not been comprehensively studied in African-Americans. We therefore sought to examine whether these validated RA risk alleles are associated with RA in an African-American population.

Source: Carolina Digital Repository (University of North Carolina at Chapel Hill)

DOI: 10.17615/97a1-s817

Authors: Brown, Elizabeth E., Thomson, Brian, Westfall, Andrew O., Moreland, Larry W., Reynolds, Richard J., Conn, Doyt L., Plenge, Robert M., Brasington, Richard D., Callahan, Leigh F., Edberg, Jeffrey C., Smith, Edwin A., Bridges, S. Louis, Hughes, Laura B., Jonas, Beth L., Kelley, James M., Padilla, Miguel A., Kimberly, Robert P.

Language: English

Topic: Rheumatoid Arthritis Research and Therapies

Subfield: Rheumatology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

Funders: National Institutes of Health, National Heart, Lung, and Blood Institute, National Institute of Arthritis and Musculoskeletal and Skin Diseases

Awards: UAB Statistical Genetics Post-Doctoral Training Program, Dissection of two rheumatoid arthritis risk loci from genome-wide studies, Meta-analysis of GWAS data to identify novel rheumatoid arthritis risk loci

OpenAlex ID: W4299940748

FWCI: 0.188

Cites:

Cited by: 1

Related to: 10