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Signalling and pharmacological properties of the P2Y14 receptor: The P2Y14 receptor

Year: 2020

Type: article

Abstract: The P2Y14 receptor is a relatively broadly expressed G protein-coupled receptor that is prominently associated with immune and inflammatory cells as well as with many epithelia. This receptor historically was thought to be activated selectively by UDP-glucose and other UDP-sugars. However, UDP is also a very potent agonist of this receptor, and may prove to be one of its most important cognate activators.

Source: Carolina Digital Repository (University of North Carolina at Chapel Hill)

DOI: 10.17615/yfzc-kq76

Authors: Lazarowski, E. R., Harden, T. K., Fricks, I. P., Sesma, J. I.

Institution: University of North Carolina at Chapel Hill

Language: English

Topic: Adenosine and Purinergic Signaling

Subfield: Physiology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: green

Funder: U.S. Public Health Service

OpenAlex ID: W4299954729

FWCI:

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