Year: 2014
Type: article
Study design: Observational Study
Abstract: BACKGROUND: Survivors of pediatric central nervous system (CNS) tumors are at risk for persistent tumor/treatment-related morbidity, physical disability and social consequences which may intrude into self-perception, vital for mental health and quality of life.Within the longitudinal Swedish CNS tumor LIFE-study, we studied the long-term impact of the childhood CNS tumor and its' treatment on self-perception in significant domains in adult survivors, by comparing outcomes with those of the general population.METHODS: The cohort included 697 Swedish survivors diagnosed between 1982 and 2001 with a primary CNS tumor.Comparison data were collected from a stratified general population random sample.Survivors and general population individuals were compared as regards selfperception in five domains: body image, sports/physical activities, peers, work, and family, and as regards a global self-esteem index.Within the survivor group, determinants of impact on self-perception were identified.RESULTS: The final sample included 528 survivors, 75.6% of the entire national study cohort.The control sample consisted of 995 individuals, 41% of 2,500 those addressed.Survivors had significantly poorer self-perception outcomes in domains of peers, work, body image, sports/physical activities, and in the global self-perception index, compared with those from the general population (all P , 0.001).Within the survivor group, female gender and persistent visible physical appearance sequelae predicted poorer outcomes in several of studied domains.CONCLUSION: Intrusion into self-perception appears as a potential long-term psychological late effect in adult survivors after pediatric CNS tumors and the brain tumor treatment.Because of this risk, patient care and psychosocial follow-up should include measures similar to what was used in this study.Paying attention to self-perception in follow-up care enables identifying, preventing, and managing of here identified adverse psychological impact of the illness on self-identity, crucially related to mental health and quality of survival.
Source: Neuro-Oncology
Authors: K. K. Boman, L. Hornquist, J. Rickardsson, B. Lannering, G. Gustafsson, N. Pitchford, E. Davis, D. Walker, D. H. Hoang, A. Pagnier, E. Cousin, K. Guichardet, I. Schiff, F. Dubois-Teklali, A. Krainik, M. B. Lazar, K. Resnik, I. T. Olsson, S. Perrin, I. B. Burtscher, J. Lundgren, A. Kahn, A. Johanson, J. Korzeniewska, B. Dembowska-Baginska, M. Perek-Polnik, K. Walsh, A. Gioia, E. Wells, R. Packer, E. D. de Speville, C. Dufour, S. Bolle, K. Giraudat, A. Longaud, V. Kieffer, J. Grill, S. Puget, D. Valteau-Couanet, L. Hetz-Pannier, M. Noulhiane, D. Chieffo, G. Tamburrini, M. Caldarelli, C. Di Rocco, K. Margelisch, M. Studer, M. Steinlin, K. Leibundgut, T. Heinks, A. Longaud-Vales, M. Chevignard, C. Dufour, J. Grill, S. Pujet, C. Sainte-Rose, D. Valteau-Couanet, G. Dellatolas, L. Kahalley, D. Grosshans, A. Paulino, M. D. Ris, M. Chintagumpala, F. Okcu, B. Moore, H. Stancel, C. Minard, D. Guffey, A. Mahajan, B. Herrington, J. Raiker, E. Manning, J. Criddle, C. Karlson, W. Guerry, J. Finlay, S. Sands, C. Dockstader, J. Skocic, E. Bouffet, S. Laughlin, U. Tabori, D. Mabbott, I. Moxon-Emre, N. Scantlebury, M. D. Taylor, E. Bouffet, D. Malkin, S. Laughlin, N. Law, T. Kumabe, J. Leonard, J. Rubin, S. Jung, S.-K. Kim, N. Gupta, W. Weiss, C. Faria, R. Vibhakar, B. Spiegler, L. Janzen, F. Liu, L. Decker, D. Mabbott, J. Lemiere, T. Vercruysse, M. Haers, K. Vandenabeele, S. Geuens, S. Jacobs, S. Van Gool, L. Riggs, J. Piscione, E. Bouffet, B. Timmons, S. Laughlin, T. Cunningham, U. Bartels, J. Skocic, F. Liu, D. Mabbott, L. Riggs, E. Bouffet, M. Chakravarty, S. Laughlin, N. Laperriere, F. Liu, J. Skocic, J. Pipitone, D. Strother, J. Hukin, C. Fryer, D. McConnell, D. Mabbott, D. E. Secco, S. Cappelletti, S. Gentile, D. Chieffo, A. Cacchione, F. Del Bufalo, S. Staccioli, A. Spagnoli, R. Messina, A. Carai, C. E. Marras, A. Mastronuzzi, T. Brinkman, G. Armstrong, C. Kimberg, A. Gajjar, D. K. Srivastava, L. Robison, M. Hudson, K. Krull, K. Hardy, S. Hostetter, E. Hwang, K. Walsh, U. Leiss, A. Bemmer, T. Pletschko, J. Grafeneder, A. Schwarzinger, P. Deimann, I. Slavc, P. Batchelder, G. Wilkening, T. Hankinson, N. Foreman, M. Handler
Language: English
Field: Medicine
Domain: Health Sciences
Open Access status: bronze
OpenAlex ID: W4300005542