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Pilot study of rosiglitazone as an in vivo probe of paclitaxel exposure: Short report

Year: 2020

Type: article

Abstract: To evaluate the use of rosiglitazone and the erythromycin breath test (ERMBT), as probes of CYP2C8 and CYP3A4, respectively, to explain inter-individual variability in paclitaxel exposure.

Source: Carolina Digital Repository (University of North Carolina at Chapel Hill)

DOI: 10.17615/f7dc-gg49

Authors: Hertz, Daniel L., Rollins, Kristan, Walko, Christine M., Herendeen, Jill, Hull, J. Heyward, Bridges, Arlene S., Watkins, Paul B., Dees, E. Claire

Institution: University of North Carolina at Chapel Hill

Language: English

Topic: Pharmacogenetics and Drug Metabolism

Subfield: Pharmacology

Field: Pharmacology, Toxicology and Pharmaceutics

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

Funders: American Foundation for Pharmaceutical Education, National Institutes of Health

Award: G9000018574

OpenAlex ID: W4300079265

FWCI:

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