Work

Microbubble tunneling in gel phantoms

Year: 2009

Type: article

Abstract: Insonified microbubbles were observed in vessels within a gel with a Young's modulus similar to that of tissue, demonstrating shape instabilities, liquid jets, and the formation of small tunnels. In this study, tunnel formulation occurred in the direction of the propagating ultrasound wave, where radiation pressure directed the contact of the bubble and gel, facilitating the activity of the liquid jets. Combinations of ultrasonic parameters and microbubble concentrations that are relevant for diagnostic imaging and drug delivery and that lead to tunnel formation were applied and the resulting tunnel formation was quantified.

Source: The Journal of the Acoustical Society of America

DOI: 10.1121/1.3097679

Authors: Charles F. Caskey, Shengping Qin, Paul A. Dayton, Katherine W. Ferrara

Institutions: University of California, Davis, University of North Carolina at Chapel Hill, North Carolina State University, Lampe Joint Department of Biomedical Engineering

Language: English

Topic: Ultrasound and Hyperthermia Applications

Subfield: Biomedical Engineering

Field: Engineering

Domain: Physical Sciences

SDG: Good health and well-being

Open Access status: green

Funders: National Institutes of Health, National Cancer Institute