Work

Regression of pressure-induced left ventricular hypertrophy is characterized by a distinct gene expression profile

Year: 2020

Type: article

Abstract: Left ventricular hypertrophy (LVH) is a highly prevalent and robust predictor of cardiovascular morbidity and mortality. Existing studies have finely detailed mechanisms involved with its development, yet clinical translation of these findings remains unsatisfactory. We propose an alternative strategy focusing on mechanisms of LVH regression rather than its progression and hypothesize that LVH regression is associated with a distinct genomic profile

Source: Carolina Digital Repository (University of North Carolina at Chapel Hill)

DOI: 10.17615/0437-xz57

Authors: Tang, Ru-hang, Moss, Nancy C., Patterson, Cam, Charles, Peter C., Stansfield, William E., Bhati, Rajendra, Rojas, Mauricio, Selzman, Craig H.

Language: English

Topic: Cardiac Fibrosis and Remodeling

Subfield: Cardiology and Cardiovascular Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

Funders: American Heart Association, Thoracic Surgery Foundation for Research and Education, Thoracic Surgery Foundation, National Institutes of Health

OpenAlex ID: W4300482856

FWCI:

Cites:

Cited by:

Related to: 10