Work

Vpr Targets TET2 for Degradation by CRL4VprBP E3 Ligase to Sustain IL-6 Expression and Enhance HIV-1 Replication

Year: 2018

Type: article

Source: Molecular Cell

DOI: 10.1016/j.molcel.2018.05.007

Authors: Lei Lv, Qi Wang, Yanping Xu, Li-Chung Tsao, Tadashi Nakagawa, Haitao Guo, Lishan Su, Yue Xiong

Institutions: University of North Carolina at Chapel Hill, UNC Lineberger Comprehensive Cancer Center

Language: English

Topic: HIV Research and Treatment

Subfield: Virology

Field: Immunology and Microbiology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: bronze

Funders: National Institutes of Health, Japan Society for the Promotion of Science, National Cancer Institute, National Institute of General Medical Sciences, National Institute of Allergy and Infectious Diseases

Awards: HIV co-infection and HCV-induced liver fibrosis in vivo, HIV-1 Replication and Pathogenesis in vivo, Analysis of RNAs associated with TDP-43 aggregation for development of novel ALS therapeutics, HIV-1 Vpr disrupts the IFN-TET-ISG pathway to promote HIV-1 infection and persistence, Epigenetic Control by Ubiquitylation, Function and Mechanism of TET Regulation of Tumor Immunity

OpenAlex ID: W2806053229

FWCI: 6.024

Cites: 30

Cited by: 100

Related to: 10