Work

A first-in-class clinical G-quadruplex-targeting drug. The bench-to-bedside translation of the fluoroquinolone QQ58 to CX-5461 (Pidnarulex)

Year: 2022

Type: review

Source: Bioorganic & Medicinal Chemistry Letters

DOI: 10.1016/j.bmcl.2022.129016

Authors: Hong Xu, Laurence H. Hurley

Institution: University of Arizona

Language: English

Topic: DNA and Nucleic Acid Chemistry

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: closed

Funder: National Cancer Institute

Award: Specific Recognition of G-quadruplexes

OpenAlex ID: W4300773325

FWCI: 1.538

Cites: 40

Cited by: 85

Related to: 10