Year: 2010
Type: article
Study design: Observational Study
Abstract: Diagnostic mammography is the primary imaging modality to diagnose breast cancer. However, few studies have evaluated variability in diagnostic mammography performance in communities, and none has done so between countries. We compared diagnostic mammography performance in community-based settings in the United States and Denmark. The performance of 93,585 diagnostic mammograms from 180 facilities contributing data to the US Breast Cancer Surveillance Consortium (BCSC) from 1999 to 2001 was compared to that of all 51,313 diagnostic mammograms performed at Danish clinics in 2000. We used the imaging workup's final assessment to determine sensitivity, specificity and an estimate of accuracy: area under the receiver-operating characteristics (ROCs) curve (AUC). Diagnostic mammography had slightly higher sensitivity in the United States (85%) than in Denmark (82%). In contrast, it had higher specificity in Denmark (99%) than in the United States (93%). The AUC was high in both countries: 0.91 in United States and 0.95 in Denmark. Denmark's higher accuracy may result from supplementary ultrasound examinations, which are provided to 74% of Danish women but only 37% to 52% of US women. In addition, Danish mammography facilities specialize in either diagnosis or screening, possibly leading to greater diagnostic mammography expertise in facilities dedicated to symptomatic patients. Performance of community-based diagnostic mammography settings varied markedly between the 2 countries, indicating that it can be further optimized.
Source: International Journal of Cancer
DOI: 10.1002/ijc.25198
Authors: Allan Jensen, Berta M. Geller, Charlotte C. Gard, Diana L. Miglioretti, Bonnie Yankaskas, Patricia A. Carney, Robert D. Rosenberg, Ilse Vejborg, Elsebeth Lynge
Institutions: University of Copenhagen, Danish Cancer Society, University of Vermont, Kaiser Permanente Washington Health Research Institute, University of Washington, University of North Carolina at Chapel Hill, Dartmouth–Hitchcock Medical Center, Oregon Health & Science University, Dartmouth Cancer Center, University of New Mexico, University of New Mexico Health Sciences Center, Copenhagen University Hospital
Language: English
Subfield: Pulmonary and Respiratory Medicine
Field: Medicine
Domain: Health Sciences
Open Access status: bronze
Funder: National Cancer Institute
Awards: San Francisco Mammography Registry-A Research Source, Carolina Mammography Registry, G339124968, G407747206, Breast Cancer Surveillance in a Defined Population, G4299498666, G4593227348, G5117928749, NEW MEXICO MAMMOGRAPHY PROJECT, G613175501, G640097384, Statistical Coordinating Center for the Breast Cancer Surveillance Consortium, BREAST CANCER SURVEILLANCE RESEARCH IN COLORADO, G7313027696, G79717682, G8622805583
OpenAlex ID: W2017087782