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IL2 Inducible T-cell Kinase, a Novel Therapeutic Target in Melanoma

Year: 2020
Type: article
Abstract: Interleukin-2 inducible T-cell kinase (ITK) promoter CpG sites are hypomethylated in melanomas compared to nevi. The expression of ITK in melanomas, however, has not been established and requires elucidation.
DOI: 10.17615/wfzp-7a23
Authors: Parrish, Eloise, Hopkinson, Dennis A., Gibbs, David C., Chan, Keefe T., Bear, James E., Nikolaishvili-Feinberg, Nana, Hao, Honglin, Zhou, Xin, Conway, Kathleen, Edmiston, Sharon N., Jordan, Jamie L., Pandey, Shaily, Miller, C. Ryan, Berkowitz, Paula, Groben, Pamela A., Hanna, Sara C., Carson, Craig C., Rubenstein, David S., Frank, Jill S., Thomas, Nancy E., Moschos, Stergios J., Ollila, David W., Sharpless, Norman E., Alldredge, Virginia D., Darr, David B., Kuan, Pei Fen
Language: English
Subfield: Oncology
Field: Medicine
Open Access status: green
Funders: V Foundation for Cancer Research, Memorial Sloan-Kettering Cancer Center, Hill's Pet Nutrition, University of North Carolina at Chapel Hill, National Cancer Institute, National Institute of Environmental Health Sciences, National Center for Advancing Translational Sciences
Awards: G1017297203, G1049756558, G2862469870, G534517478, G5543907513, G5626962992, G6103388094, Cancer Center Support Grant
OpenAlex ID: W4301243302
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