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Influenza enhances caspase-1 in bronchial epithelial cells from asthmatics and is associated with pathogenesis

Year: 2020

Type: article

Abstract: The leading cause of asthma exacerbation is respiratory viral infection. Innate antiviral defense pathways are altered in the asthmatic epithelium, yet involvement of inflammasome signaling in virus-induced asthma exacerbation is not known.

Source: Carolina Digital Repository (University of North Carolina at Chapel Hill)

DOI: 10.17615/fgkc-wt96

Authors: Peden, David B., Mueller, Loretta, Brighton, Luisa E., Fry, Rebecca C., Xiang, Zhidan, Rager, Julia E., Jaspers, Ilona, Bauer, Rebecca N.

Institution: University of North Carolina at Chapel Hill

Language: English

Topic: Asthma and respiratory diseases

Subfield: Physiology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

Funders: U.S. Environmental Protection Agency, University of North Carolina at Chapel Hill, National Institute of Environmental Health Sciences

Awards: G1040551009, G5000067424

OpenAlex ID: W4301433173

FWCI:

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