Work

Quantitation of extracellular UTP using a sensitive enzymatic assay

Year: 2020

Type: article

Abstract: The physiological significance of ATP and ADP as extracellular signalling molecules is well established (Burnstock, 1972; Gordon, 1986; Dubyak & El-Moatassim, 1993). Both molecules are released in a regulated manner from excitatory and non-excitatory cells, and these released nucleotides interact with both the P2X receptor subfamily of ligand-gated ion channel receptors and the P2Y receptor subfamily of G protein-coupled receptors (Burnstock & Kennedy, 1985; Abbracchio et al., 1996; Fredholm et al., 1997).

Source: Carolina Digital Repository (University of North Carolina at Chapel Hill)

DOI: 10.17615/m23h-6d79

Authors: Lazarowski, Eduardo R., Harden, T. Kendall

Institution: University of North Carolina at Chapel Hill

Language: English

Topic: Adenosine and Purinergic Signaling

Subfield: Physiology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: green

Funder: U.S. Public Health Service

OpenAlex ID: W4301517449

FWCI:

Cites:

Cited by: 2

Related to: 10