Year: 2022
Type: editorial
Abstract: Editorial on the Research Topic Cardiovascular diseases related to diabetes and obesity volume II Metabolic diseases are multifactorial, multifaceted, and even intertwined making understanding the etiopathogenesis of such diseases more complex than originally thought.This concept of intimately intertwined health conditions is exemplified in the relationship between obesity, diabetes, and cardiovascular diseases (CVDs), of which the prevalence of all three diseases are growing in parallel with one another.Nearly tripling in prevalence since 1975, obesity is considered a leading global health concern and continues be the number one risk factor for diabetes and CVDs (1).Despite our advances at the bench and in the clinic, approximately 17.9 million people die each year from CVDs, accounting for 32% of all deaths globally (2).Therefore, it is imperative to rigorously investigate the underlying mechanisms involved in the pathogenesis of obesity-and diabetes-related cardiovascular events to develop more effective, targeted therapies aimed at prevention and attenuation of disease progression.Reflective of the significance of this topic, a second volume of this special issue has been created, further compiling recent clinical, pre-clinical and basic research studies as well as review articles aimed at filling the knowledge gaps and expanding our understanding of the complicated and intertwined relationship between obesity, diabetes, and CVDs.The multifactorial, intertwined nature of metabolic diseases has become increasingly apparent.In fact, the term "metabolic syndrome" is used to describe a group of conditions that work together to increase the risk of diabetes and CVDs.It is pertinent to note obesity is the main risk factor for metabolic syndrome.A major contributor to CVDs is premature myocardial infarction (PMI), referring to myocardial infarction that occurs in men less than 55 years old and women less than 65 years old.In an observational study by Gao et al. (2022) 772 patients less than 45 years old diagnosed with acute myocardial infarction were divided into groups based on whether they had Frontiers in Endocrinology frontiersin.org
Source: Frontiers in Endocrinology
Authors: Jamie L. Young, Ying Xin, Mohanraj Rajesh, Lu Cai
Language: English
Subfield: Endocrinology, Diabetes and Metabolism
Field: Medicine
Domain: Health Sciences
Open Access status: gold
Estimated APC paid: $2,950
OpenAlex ID: W4301586610